Anti-Phospho-Histone H3 (pT11) Antibody (N123/19) (HX988023)

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50ug
100ug
1mg

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Datasheet

Overview

Catalog No.

HX988023

Description

Anti-Phospho-Histone H3 (pT11) Antibody (N123/19) [N123/19] (HX988023) is a mouse monoclonal antibody detecting Histone H3/j in IHC, IP, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Rat

Applications

IHC, IP, WB

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

N123/19

Clonality

Monoclonal

Target

Histone H3/j, Histone H3/b, Histone H3/d, Histone H3/c, HIST1H3B, H3FH, Histone H3/f, H3FF, H3FK, HIST1H3G, H3FL, H3FB, HIST1H3D, Histone H3/a, H3FI, Histone H3/i, H3FD, HIST1H3A, Histone H3/h, HIST1H3I, HIST1H3E, HIST1H3H, HIST1H3J, H3C1, H3FC HIST1H3C, H3FA, Histone H3.1, H3FJ, Histone H3/l, Histone H3/k, HIST1H3F

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P68431

RRID

Anti-Phospho-Histone H3 (pT11) Antibody (N123/19) (abinScience Cat# HX988023, RRID:AB_3725767)

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Histone H3.1 (p-Histone H3) is a ~15 kDa protein. Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Note

For research use only.

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