Anti-Mouse CD282/TLR2 Recombinant Nanobody (SAA0821) (MT188013)

Name: Anti-Mouse CD282/TLR2 Recombinant Nanobody (SAA0821)
Brand: abinScience
SKU: MT188013
Price: 191 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD): --

Spec:

50ug
100ug
1mg

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

MT188013

Description

Anti-Mouse CD282/TLR2 Nanobody (SAA0821) [SAA0821] (MT188013) is a alpaca monoclonal antibody detecting CD282 in Blocking, ELISA. Suitable for Mouse.

Species reactivity

Mouse

Applications

Blocking, ELISA

Host species

Alpaca

Clonality

Monoclonal

Isotype

VHH-8His-Cys-tag

Clone ID

SAA0821

Target

Toll-like receptor 2, CD282, Tlr2

Endotoxin level

< 10 EU/mg as determined by LAL method.

Purity

>95% as determined by SDS-PAGE.

Purification

Purified by Nickel column.

Accession

Q9QUN7

Form

Liquid

Storage buffer

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Toll-like receptor 2 (CD282/TLR2) is a ~89 kDa protein. Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also activate immune cells and promote apoptosis in response to the lipid moiety of lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6.

1. Jin, MS. et al. (2007) Cell 130, 1071-82. PMID: 17889651

2. Lancioni, CL. et al. (2011) Infection and immunity 79, 663-73. PMID: 21078852

3. Brightbill, HD. et al. (1999) Science (New York, N.Y.) 285, 732-6. PMID: 10426995

4. Aliprantis, AO. et al. (1999) Science (New York, N.Y.) 285, 736-9. PMID: 10426996

5. Bulut, Y. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 987-94. PMID: 11441107

6. Jung, SB. et al. (2006) Infection and immunity 74, 2686-96. PMID: 16622205

7. Drage, MG. et al. (2009) Cellular immunology 258, 29-37. PMID: 19362712

8. Bulut, Y. et al. (2005) The Journal of biological chemistry 280, 20961-7. PMID: 15809303

9. Triantafilou, M. et al. (2006) The Journal of biological chemistry 281, 31002-11. PMID: 16880211

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Mouse CD282/TLR2 Nanobody (SAA0821)

References

Datasheet

Anti-Mouse CD282/TLR2 Recombinant Nanobody (SAA0821).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Mouse CD282/TLR2 Recombinant Nanobody (SAA0821) (MT188013)

Overview

Images

References

Datasheet

SDS