Anti-SARS-CoV-2 NP/Nucleoprotein Nanobody (SAA0961) (VK805043)

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50ug
100ug
1mg

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Datasheet

Overview

Catalog No.

VK805043

Description

Anti-SARS-CoV-2 NP/Nucleoprotein Nanobody (SAA0961) [SAA0961] (VK805043) is a alpaca monoclonal antibody detecting Nucleoprotein in ELISA.

Species reactivity

Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) (SARS-CoV-2)

Applications

ELISA

Host species

Alpaca

Isotype

VHH-8His-Cys-tag

Clone ID

SAA0961

Clonality

Monoclonal

Target

Nucleoprotein, N, Nucleocapsid protein, NC, Protein N, N

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Purified by Nickel column.

Accession

P0DTC9

RRID

Anti-SARS-CoV-2 NP/Nucleoprotein Nanobody (SAA0961) (abinScience Cat# VK805043, RRID:AB_3726797)

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Nucleoprotein (NP) is a ~45 kDa protein. Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Attenuates the stress granules formation by reducing host G3BP1 access to host mRNAs under stress conditions.

1. Dinesh, DC. et al. (2020) PLoS pathogens 16, e1009100. PMID: 33264373

2. Nabeel-Shah, S. et al. (2022) iScience 25, 103562. PMID: 34901782

3. Dolliver, SM. et al. (2022) PLoS pathogens 18, e1011041. PMID: 36534661

Note

For research use only.

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