InVivoMAb Anti-RSV G/Major surface glycoprotein G Antibody (3G12) (VK562030)

Name: InVivoMAb Anti-RSV G/Major surface glycoprotein G Antibody (3G12)
Brand: abinScience
SKU: VK562030
Price: 370 USD
Availability: InStock

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100ug
1mg

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Overview
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References
Datasheet
SDS

Overview

Catalog No.	VK562030
Description	InVivoMAb Anti-HRSV G/Major surface glycoprotein G Antibody (3G12) [3G12] (VK562030) is a human monoclonal antibody detecting Major surface glycoprotein G in ELISA, Neutralization, WB. Highlights ●Multi-Application — Validated across multiple applications.
Species reactivity	Human respiratory syncytial virus A (strain A2)
Applications	ELISA, Neutralization, WB
Host species	Human
Isotype	IgG1, kappa
Clone ID	3G12
Clonality	Monoclonal
Target	Major surface glycoprotein G, Attachment glycoprotein G, Membrane-bound glycoprotein, mG, Mature secreted glycoprotein G, Mature sG, G
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Associated products	pH 7.4 Dilution Buffer
Purification	Protein A/G purified from cell culture supernatant.
Accession	P03423
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Major surface glycoprotein G is a ~32 kDa protein. Attaches the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection. Interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection. Unlike the other paramyxovirus attachment proteins, lacks both neuraminidase and hemagglutinating activities (Probable). 1. Feldman, SA. et al. (1999) Journal of virology 73, 6610-7. PMID: 10400758 2. Feldman, SA. et al. (2000) Journal of virology 74, 6442-7. PMID: 10864656 3. Levine, S. et al. (1987) The Journal of general virology 68 ( Pt 9), 2521-4. PMID: 3655746 4. Tripp, RA. et al. (2001) Nature immunology 2, 732-8. PMID: 11477410 5. Jeong, KI. et al. (2015) PloS one 10, e0130517. PMID: 26107373 6. Johnson, SM. et al. (2015) PLoS pathogens 11, e1005318. PMID: 26658574
Note	For research use only. Not suitable for clinical or therapeutic use.

Images

SDS-PAGE

SDS-PAGE for InVivoMAb Anti-HRSV G/Major surface glycoprotein G Antibody (3G12)
Bioactivity

Detects recombinant HRSV G/Major surface glycoprotein G (Catalog No: VK562011) in indirect ELISA