Anti-Human TAFA5/FAM19A5 Antibody (SAA1465) (HP986013)

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50ug
100ug
1mg

Number:

Overview
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Datasheet

Overview

Catalog No.

HP986013

Description

Anti-Human TAFA5/FAM19A5 Antibody (SAA1465) [SAA1465] (HP986013) is a mouse monoclonal antibody detecting FAM19A5 in ELISA, WB. Suitable for Human.

Species reactivity

Human

Applications

ELISA, WB

Host species

Mouse

Isotype

IgG2a

Clone ID

SAA1465

Clonality

Monoclonal

Target

Chemokine-like protein TAFA-5, TAFA5, FAM19A5

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q7Z5A7

RRID

Anti-Human TAFA5/FAM19A5 Antibody (SAA1465) (abinScience Cat# HP986013, RRID:AB_3727121)

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Chemokine-like protein TAFA-5 (TAFA5/FAM19A5) is a ~14 kDa protein. Acts as a chemokine-like protein by regulating cell proliferation and migration through activation of G protein-coupled receptors (GPCRs), such as S1PR2 and FPR2. Stimulates chemotactic migration of macrophages mediated by the MAPK3/ERK1 and AKT1 pathway. Blocks TNFSF11/RANKL-induced osteoclast formation from macrophages by inhibiting up-regulation of osteoclast fusogenic and differentiation genes. Stimulation of macrophage migration and inhibition of osteoclast formation is mediated via GPCR FPR2. Acts as an adipokine by negatively regulating vascular smooth muscle cell (VSMC) proliferation and migration in response to platelet-derived growth factor stimulation via GPCR S1PR2 and G protein GNA12/GNA13-transmitted RHOA signaling.

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human TAFA5/FAM19A5 Antibody (SAA1465)

References

Datasheet

Anti-Human TAFA5/FAM19A5 Antibody (SAA1465).pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human TAFA5/FAM19A5 Antibody (SAA1465) (HP986013)

Overview

Images

References

Datasheet

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