Anti-Human SH3PXD2A Recombinant Antibody (SAA1469) (HP455013)

Name: Anti-Human SH3PXD2A Recombinant Antibody (SAA1469)
Brand: abinScience
SKU: HP455013
Price: 196 USD
Availability: InStock

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100ug
1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HP455013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1469

Clonality

Monoclonal

Target

SH3PXD2A, FISH, SH3MD1, TKS5, SH3 and PX domain-containing protein 2A, Adapter protein TKS5, Five SH3 domain-containing protein, SH3 multiple domains protein 1, Tyrosine kinase substrate with five SH3 domains

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q5TCZ1

RRID

Anti-Human SH3PXD2A Antibody (SAA1469) (abinScience Cat# HP455013, RRID:AB_3727145)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

SH3 and PX domain-containing protein 2A (SH3PXD2A) is a ~125 kDa protein. Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.

1. Jacob, A. et al. (2016) Journal of cell science 129, 4341-4353. PMID: 27789576

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human SH3PXD2A Antibody (SAA1469)

References

Datasheet

Anti-Human SH3PXD2A Recombinant Antibody (SAA1469).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human SH3PXD2A Recombinant Antibody (SAA1469) (HP455013)

Overview

Images

References

Datasheet

SDS

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