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InVivoMAb Anti-HSV-1/HHV-1 gB/Envelope glycoprotein B Antibody (Fd79) (VK520020)

InVivoMAb Anti-HSV-1/HHV-1 gB/Envelope glycoprotein B Antibody (Fd79)
InVivoMAb Anti-HSV-1/HHV-1 gB/Envelope glycoprotein B Antibody (Fd79)
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  • 100ug
  • 1mg
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Overview
Catalog No.VK520020
Description
InVivoMAb Anti-HSV1/HHV1 gB/Envelope glycoprotein B (Fd79) [Fd79] (VK520020) is a human monoclonal antibody detecting Envelope glycoprotein B in Blocking, ELISA, FCM.
Highlights
  • Multi-Application — Validated across multiple applications.
  • Flow Cytometry — Validated for flow cytometry applications.
Species reactivityHuman herpesvirus 1 (HHV-1) (Human herpes simplex virus 1) (HSV-1)
ApplicationsBlocking, ELISA, FCM
Host speciesHuman
IsotypeIgG1
Clone IDFd79
Clonality Monoclonal
Target Envelope glycoprotein B, gB, UL27
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Associated products pH 7.4 Dilution Buffer
Purification Protein A/G purified from cell culture supernatant.
Accession P06436
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Envelope glycoprotein B (gB) is a ~100 kDa protein. Envelope glycoprotein that forms spikes at the surface of virion envelope and binds to the host cell entry receptors MYH9/NMMHC-IIA and MYH10/NMMHC-IIB, promoting the virus entry into host cells. Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans. Involved in fusion of viral and cellular membranes leading to virus entry into the host cell: following initial binding to its host cell entry receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress. Also plays a role, together with gK, in virus-induced cell-to-cell fusion (syncytia formation).

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • InVivoMAb Anti-HSV-1/HHV-1 gB/Envelope glycoprotein B Antibody (Fd79)

    SDS-PAGE

    SDS-PAGE for InVivoMAb Anti-HSV1/HHV1 gB/Envelope glycoprotein B (Fd79)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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