Anti-Human CLPTM1 Antibody (SAA1543) (HF796013)

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50ug
100ug
1mg

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Overview
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Datasheet

Overview

Catalog No.

HF796013

Description

Anti-Human CLPTM1 Antibody (SAA1543) [SAA1543] (HF796013) is a mouse monoclonal antibody detecting CLPTM1 in ELISA. Suitable for Human.

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1543

Clonality

Monoclonal

Target

CLPTM1, Cleft lip and palate transmembrane protein 1

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O96005

RRID

Anti-Human CLPTM1 Antibody (SAA1543) (abinScience Cat# HF796013, RRID:AB_3727304)

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Putative lipid scramblase CLPTM1 is a ~76 kDa protein. Involved in GABAergic but not glutamatergic transmission. Binds and traps GABAA receptors in the endoplasmic reticulum (ER). Modulates postsynaptic GABAergic transmission, and therefore inhibitory neurotransmission, by reducing the plasma membrane expression of these receptors. Altered GABAergic signaling is one among many causes of cleft palate. Might function as a lipid scramblase, translocating lipids in membranes from one leaflet to the other one.

1. Liu, YS. et al. (2018) The Journal of cell biology 217, 585-599. PMID: 29255114

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human CLPTM1 Antibody (SAA1543)

References

Datasheet

Anti-Human CLPTM1 Antibody (SAA1543).pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human CLPTM1 Antibody (SAA1543) (HF796013)

Overview

Images

References

Datasheet

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