

| Catalog No. | HW647013 | ||||
|---|---|---|---|---|---|
| Species reactivity | Human | ||||
| Applications | ELISA | ||||
| Host species | Mouse | ||||
| Isotype | IgG2a, kappa | ||||
| Clone ID | SAA1643 | ||||
| Clonality | Monoclonal | ||||
| Target | hASH1, ASH1, Achaete-scute homolog 1, BHLHA46, ASH-1, ASCL1, Class A basic helix-loop-helix protein 46, HASH1, bHLHa46 | ||||
| Endotoxin level | Please contact with the lab for this information. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | P50553 | ||||
| RRID | Anti-Human ASCL1 Antibody (SAA1643) (abinScience Cat# HW647013, RRID:AB_3727404) |
||||
| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
||||
| Product Usage Information |
| ||||
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Background | Achaete-scute homolog 1 (ASCL1) is a ~25 kDa protein. Transcription factor that plays a key role in neuronal differentiation: acts as a pioneer transcription factor, accessing closed chromatin to allow other factors to bind and activate neural pathways. Directly binds the E box motif (5'-CANNTG-3') on promoters and promotes transcription of neuronal genes. The combination of three transcription factors, ASCL1, POU3F2/BRN2 and MYT1L, is sufficient to reprogram fibroblasts and other somatic cells into induced neuronal (iN) cells in vitro. Plays a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Essential for the generation of olfactory and autonomic neurons. | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human ASCL1 Antibody (SAA1643)
Contact us for custom quotes, bulk requests and any other issues.
Mail: support@abinScience.com


+86-27-87433958
Building C, No. 666, Shen Dun Si Lu, Wuhan, 430206, China
中文
English
한국어
日本語
Español
Français
Русский