Anti-Human DAB2IP Recombinant Antibody (SAA1697) (HV442013)

Name: Anti-Human DAB2IP Recombinant Antibody (SAA1697)
Brand: abinScience
SKU: HV442013
Price: 196 USD
Availability: InStock

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50ug
100ug
1mg

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HV442013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1697

Clonality

Monoclonal

Target

DOC-2/DAB-2 interactive protein, DAB2IP, KIAA1743, Disabled homolog 2-interacting protein, AF9Q34, AIP1, DAB2 interaction protein, DAB2-interacting protein, ASK-interacting protein 1, AIP-1

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q5VWQ8

RRID

Anti-Human DAB2IP Antibody (SAA1697) (abinScience Cat# HV442013, RRID:AB_3727458)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Disabled homolog 2-interacting protein (DAB2IP) is a ~131 kDa protein. Functions as a scaffold protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Involved in several processes such as innate immune response, inflammation and cell growth inhibition, apoptosis, cell survival, angiogenesis, cell migration and maturation. Also plays a role in cell cycle checkpoint control; reduces G1 phase cyclin levels resulting in G0/G1 cell cycle arrest. Mediates signal transduction by receptor-mediated inflammatory signals, such as the tumor necrosis factor (TNF), interferon (IFN) or lipopolysaccharide (LPS). Modulates the balance between phosphatidylinositol 3-kinase (PI3K)-AKT-mediated cell survival and apoptosis stimulated kinase (MAP3K5)-JNK signaling pathways; sequesters both AKT1 and MAP3K5 and counterbalances the activity of each kinase by modulating their phosphorylation status in response to pro-inflammatory stimuli.

1. Luo, X. et al. (2017) Oncotarget 8, 85415-85427. PMID: 29156729

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human DAB2IP Antibody (SAA1697)

References

Datasheet

Anti-Human DAB2IP Recombinant Antibody (SAA1697).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human DAB2IP Recombinant Antibody (SAA1697) (HV442013)

Overview

Images

References

Datasheet

SDS

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