Anti-Human CMKLR1 Recombinant Antibody (SAA1892) (HA971013)

Name: Anti-Human CMKLR1 Recombinant Antibody (SAA1892)
Brand: abinScience
SKU: HA971013
Price: 196 USD
Availability: InStock

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50ug
100ug
1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HA971013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1892

Clonality

Monoclonal

Target

DEZ, CMKLR1, G-protein coupled receptor DEZ, G-protein coupled receptor ChemR23, CHEMR23, Chemokine-like receptor 1

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q99788

RRID

Anti-Human CMKLR1 Antibody (SAA1892) (abinScience Cat# HA971013, RRID:AB_3727656)
_x005F_x000D_

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Chemerin-like receptor 1 (CMKLR1) is a ~42 kDa protein. Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 initiates activation of G proteins G(i)/G(o) and beta-arrestin pathways inducing cellular responses via second messenger pathways such as intracellular calcium mobilization, phosphorylation of MAP kinases MAPK1/MAPK3 (ERK1/2), TYRO3, MAPK14/P38MAPK and PI3K leading to multifunctional effects, like reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism.

1. De Henau, O. et al. (2016) PloS one 11, e0164179. PMID: 27716822

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human CMKLR1 Antibody (SAA1892)

References

Datasheet

Anti-Human CMKLR1 Recombinant Antibody (SAA1892).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human CMKLR1 Recombinant Antibody (SAA1892) (HA971013)

Overview

Images

References

Datasheet

SDS

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