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Anti-Human NME7 Recombinant Antibody (SAA1925) (HA033013)

Anti-Human NME7 Recombinant Antibody (SAA1925)
Anti-Human NME7 Recombinant Antibody (SAA1925)
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Overview
Catalog No.HA033013
Species reactivityHuman
ApplicationsELISA
Host speciesMouse
IsotypeIgG2a, kappa
Clone IDSAA1925
Clonality Monoclonal
Target NME7, Nucleoside diphosphate kinase 7, NDP kinase 7, NDK 7, nm23-H7
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q9Y5B8
RRID

Anti-Human NME7 Antibody (SAA1925) (abinScience Cat# HA033013, RRID:AB_3727689)
_x005F_x000D_

Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Nucleoside diphosphate kinase 7 (NME7) is a ~42 kDa protein. Possesses an intrinsic kinase activity. Phosphorylates GSK3B at 'Ser-9', leading to the activation of Wnt/beta-catenin signaling. Additionally, exhibits a 3'-5'-DNA exonuclease activity that removes single nucleotides from the 3' terminus of single-stranded DNA substrates and digests overhanging mismatched 3' termini from double-stranded DNA substrates, possibly participating in DNA nucleolytic processing. In vitro, does not seem to have nucleoside diphosphate kinase activity. Functional component of the gamma-tubulin ring complex, implicated in the regulation of its microtubule-nucleating activity in centrosomes, in a kinase activity-dependent manner.

1. Liu, P. et al. (2014) Molecular biology of the cell 25, 2017-25. PMID: 24807905
2. Ren, X. et al. (2022) Cancer research 82, 60-74. PMID: 34764205
3. Yoon, JH. et al. (2005) Biochemistry 44, 15774-86. PMID: 16313181
4. Ji, M. et al. (2025) Life science alliance 8. PMID: 39824631
5. Gui, M. et al. (2022) Proceedings of the National Academy of Sciences of the United States of America 119, e2207605119. PMID: 36191189
Note For research use only.
Images
  • Anti-Human NME7 Recombinant Antibody (SAA1925)

    SDS-PAGE

    SDS-PAGE for Anti-Human NME7 Antibody (SAA1925)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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