Anti-Human ABCC3/MRP3 Recombinant Antibody (SAA1949) (HT036013)

Name: Anti-Human ABCC3/MRP3 Recombinant Antibody (SAA1949)
Brand: abinScience
SKU: HT036013
Price: 196 USD
Availability: InStock

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1mg

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HT036013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1949

Clonality

Monoclonal

Target

ABCC3, MRP3, MOAT-D, CMOAT2, Canalicular multispecific organic anion transporter 2, ATP-binding cassette sub-family C member 3, Multidrug resistance-associated protein 3, Multi-specific organic anion transporter D, MLP2

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O15438

RRID

Anti-Human ABCC3/MRP3 Antibody (SAA1949) (abinScience Cat# HT036013, RRID:AB_3727713)
_x005F_x000D_

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

ATP-binding cassette sub-family C member 3 (ABCC3/MRP3) is a ~169 kDa protein. ATP-dependent transporter of the ATP-binding cassette (ABC) family that binds and hydrolyzes ATP to enable active transport of various substrates including many drugs, toxicants and endogenous compound across cell membranes. Transports glucuronide conjugates such as bilirubin diglucuronide, estradiol-17-beta-o-glucuronide and GSH conjugates such as leukotriene C4 (LTC4). Transports also various bile salts (taurocholate, glycocholate, taurochenodeoxycholate-3-sulfate, taurolithocholate- 3-sulfate). Does not contribute substantially to bile salt physiology but provides an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes. May contribute to regulate the transport of organic compounds in testes across the blood-testis-barrier (Probable).

1. Kool, M. et al. (1999) Proceedings of the National Academy of Sciences of the United States of America 96, 6914-9. PMID: 10359813

2. Zelcer, N. et al. (2001) The Journal of biological chemistry 276, 46400-7. PMID: 11581266

3. Lee, YM. et al. (2004) Pharmacogenetics 14, 213-23. PMID: 15083066

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human ABCC3/MRP3 Antibody (SAA1949)

References

Datasheet

Anti-Human ABCC3/MRP3 Recombinant Antibody (SAA1949).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human ABCC3/MRP3 Recombinant Antibody (SAA1949) (HT036013)

Overview

Images

References

Datasheet

SDS

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