Anti-Human PLA2R1/PLA2R Recombinant Antibody (SAA1959) (HC624013)

Name: Anti-Human PLA2R1/PLA2R Recombinant Antibody (SAA1959)
Brand: abinScience
SKU: HC624013
Price: 196 USD
Availability: InStock

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100ug
1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HC624013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1959

Clonality

Monoclonal

Target

PLA2R, 180 kDa secretory phospholipase A2 receptor, Secretory phospholipase A2 receptor, PLA2-R, M-type receptor, C-type lectin domain family 13 member C, Soluble PLA2-R, PLA2R1, Soluble PLA2R, CLEC13C

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q13018

RRID

Anti-Human PLA2R1/PLA2R Antibody (SAA1959) (abinScience Cat# HC624013, RRID:AB_3727723)
_x005F_x005F_x000D_

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Secretory phospholipase A2 receptor (PLA2R1/PLA2R) is a ~168 kDa protein. Receptor for secretory phospholipase A2 (sPLA2). Acts as a receptor for phospholipase sPLA2-IB/PLA2G1B but not sPLA2-IIA/PLA2G2A. Also able to bind to snake PA2-like toxins. Although its precise function remains unclear, binding of sPLA2 to its receptor participates in both positive and negative regulation of sPLA2 functions as well as clearance of sPLA2. Binding of sPLA2-IB/PLA2G1B induces various effects depending on the cell type, such as activation of the mitogen-activated protein kinase (MAPK) cascade to induce cell proliferation, the production of lipid mediators, selective release of arachidonic acid in bone marrow-derived mast cells.

1. Granata, F. et al. (2005) Journal of immunology (Baltimore, Md. : 1950) 174, 464-74. PMID: 15611272

2. Ancian, P. et al. (1995) The Journal of biological chemistry 270, 8963-70. PMID: 7721806

3. Pan, Y. et al. (2014) Scientific reports 4, 6660. PMID: 25335547

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human PLA2R1/PLA2R Antibody (SAA1959)

References

Datasheet

Anti-Human PLA2R1/PLA2R Recombinant Antibody (SAA1959).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human PLA2R1/PLA2R Recombinant Antibody (SAA1959) (HC624013)

Overview

Images

References

Datasheet

SDS

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