

| Catalog No. | HV781013 | ||||
|---|---|---|---|---|---|
| Species reactivity | Human | ||||
| Applications | ELISA | ||||
| Host species | Mouse | ||||
| Isotype | IgG2a, kappa | ||||
| Clone ID | SAA1966 | ||||
| Clonality | Monoclonal | ||||
| Target | TRAIL-R4, TRAIL receptor 4, DcR2, TRAIL receptor with a truncated death domain, TRUNDD, DCR2, Decoy receptor 2, TNF-related apoptosis-inducing ligand receptor 4, TRAILR4, TNFRSF10D, Tumor necrosis factor receptor superfamily member 10D, CD264 | ||||
| Endotoxin level | Please contact with the lab for this information. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | Q9UBN6 | ||||
| RRID | Anti-Human CD264/TNFRSF10D/TRAIL-R4 Antibody (SAA1966) (abinScience Cat# HV781013, RRID:AB_3727730) |
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| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
| ||||
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Background | Tumor necrosis factor receptor superfamily member 10D (CD264/TNFRSF10D) is a ~41 kDa protein. Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway. 1. Degli-Esposti, MA. et al. (1997) Immunity 7, 813-20. PMID: 9430226 2. Pan, G. et al. (1998) FEBS letters 424, 41-5. PMID: 9537512 3. Marsters, SA. et al. (1997) Current biology : CB 7, 1003-6. PMID: 9382840 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human CD264/TNFRSF10D/TRAIL-R4 Antibody (SAA1966)


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