Anti-Human CALCA Antibody (SAA2004) (HY028013)

Datasheet Share product Copy info

Price(USD): $

Spec:

20ug
50ug
100ug
1mg

Number:

Overview
Images
References
Datasheet

Overview

Catalog No.

HY028013

Description

Anti-Human CALCA Antibody (SAA2004) [SAA2004] (HY028013) is a human monoclonal antibody detecting CALCA in ELISA, WB. Suitable for Human.

Species reactivity

Human

Applications

ELISA, WB

Host species

Human

Isotype

IgG4, kappa

Clone ID

SAA2004

Clonality

Monoclonal

Target

Alpha-type CGRP, CALC1, CALCA, CGRP-I, CGRP1, Calcitonin gene-related peptide 1, Calcitonin gene-related peptide I

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P06881

RRID

Anti-Human CALCA Antibody (SAA2004) (abinScience Cat# HY028013, RRID:AB_3727916)

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Calcitonin gene-related peptide 1 (CGRP1) is a ~13 kDa protein. CGRP1/CALCA is a peptide hormone that induces vasodilation mediated by the CALCRL-RAMP1 receptor complex. Dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP. CGRP1 can also bind and activate CALCR-RAMP1 (AMYR1) receptor complex.

1. Kitamura, K. et al. (1992) Biochemical and biophysical research communications 185, 134-41. PMID: 1318039

2. Josephs, TM. et al. (2021) Science (New York, N.Y.) 372. PMID: 33602864

3. McLatchie, LM. et al. (1998) Nature 393, 333-9. PMID: 9620797

4. Petermann, JB. et al. (1987) The Journal of biological chemistry 262, 542-5. PMID: 3492492

5. Cao, J. et al. (2024) Biochemistry 63, 1089-1096. PMID: 38603770

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human CALCA Antibody (SAA2004).

References

Datasheet

Anti-Human CALCA Antibody (SAA2004).pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human CALCA Antibody (SAA2004) (HY028013)

Overview

Images

References

Datasheet

Quick access

Contact Us