Anti-DENV-2 NSP5/NS5 Antibody (3B4) (VK651073)

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50ug
100ug
1mg

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Datasheet

Overview

Catalog No.

VK651073

Description

Anti-DENV-2 NSP5/NS5 Antibody (3B4) [3B4] (VK651073) is a human monoclonal antibody detecting RNA-directed RNA polymerase NS5 in ELISA.

Species reactivity

Dengue virus type 2 (strain 16681-PDK53) (DENV-2)

Applications

ELISA

Host species

Human

Isotype

IgG1, kappa

Clone ID

3B4

Clonality

Monoclonal

Target

Genome polyprotein, RNA-directed RNA polymerase NS5

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P29991

RRID

Anti-DENV-2 NSP5/NS5 Antibody (3B4) (abinScience Cat# VK651073, RRID:AB_3729166)

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Genome polyprotein (NSP5/NS5) is a ~379 kDa protein. Capsid protein C self-assembles to form an icosahedral capsid about 30 nm in diameter. The capsid encapsulates the genomic RNA (Probable). Plays a role in virus budding by binding to the cell membrane and gathering the viral RNA into a nucleocapsid that forms the core of a mature virus particle. During virus entry, may induce genome penetration into the host cytoplasm after hemifusion induced by the surface proteins. Can migrate to the cell nucleus where it modulates host functions.

Note

For research use only.

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