Anti-Norovirus VP1/P domain Recombinant Nanobody (Nano-85) (VK441043)

Name: Anti-Norovirus VP1/P domain Recombinant Nanobody (Nano-85)
Brand: abinScience
SKU: VK441043
Price: 126 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

VK441043

Description

Anti-Norovirus/Norwalk virus Capsid protein/VP1 Nanobody (Nano-85) [Nano-85] (VK441043) is a alpaca monoclonal antibody detecting Capsid protein in ELISA. Suitable for Norwalk virus.

Species reactivity

Norwalk virus (NoV)

Applications

ELISA

Host species

Alpaca

Clonality

Monoclonal

Isotype

VHH-8His-Cys-tag

Clone ID

Nano-85

Target

Capsid protein, VP1

Endotoxin level

< 10 EU/mg as determined by LAL method.

Purity

>95% as determined by SDS-PAGE.

Purification

Purified by Nickel column.

Accession

Q5F4T5, K4LM89, B5BTR4

Form

Liquid

Storage buffer

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Capsid protein VP1 is a ~56 kDa protein. Capsid protein self assembles to form an icosahedral capsid with a T=3 symmetry, about 38 nm in diameter, and consisting of 180 capsid proteins. A smaller form of capsid with a diameter of 23 nm might be capsid proteins assembled as icosahedron with T=1 symmetry. The capsid encapsulates the genomic RNA and is decorated with VP2 proteins. Attaches virion to target cells by binding histo-blood group antigens (HBGAs) present on gastroduodenal epithelial cells.

1. Prasad, BV. et al. (1999) Science (New York, N.Y.) 286, 287-90. PMID: 10514371

2. Jung, J. et al. (2019) Proceedings of the National Academy of Sciences of the United States of America 116, 12828-12832. PMID: 31182604

3. White, LJ. et al. (1997) Journal of virology 71, 8066-72. PMID: 9311906

4. Marionneau, S. et al. (2002) Gastroenterology 122, 1967-77. PMID: 12055602

5. Huang, P. et al. (2003) The Journal of infectious diseases 188, 19-31. PMID: 12825167

6. Tan, M. et al. (2006) Journal of virology 80, 7322-31. PMID: 16840313

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Norovirus/Norwalk virus Capsid protein/VP1 Nanobody (Nano-85)

References

Datasheet

Anti-Norovirus VP1/P domain Recombinant Nanobody (Nano-85).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Norovirus VP1/P domain Recombinant Nanobody (Nano-85) (VK441043)

Overview

Images

References

Datasheet

SDS