

| Catalog No. | AY286013 | ||||
|---|---|---|---|---|---|
| Description |
Anti-Trastuzumab Idiotypic Recombinant Antibody (1HE) (AY286013) is a human monoclonal antibody detecting Trastuzumab in Blocking, ELISA. Suitable for General.
Highlights
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| Species reactivity | General | ||||
| Applications | Blocking, ELISA | ||||
| Host species | Human | ||||
| Clonality | Monoclonal | ||||
| Isotype | VHH-hFc | ||||
| Clone ID | 1HE | ||||
| Expression system | Mammalian cells | ||||
| Immunogen | Trastuzumab | ||||
| Target | Trastuzumab | ||||
| Endotoxin level | < 10 EU/mg as determined by LAL method. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | CAS: 180288-69-1 | ||||
| RRID | Anti-Trastuzumab Idiotypic Antibody (1HE) (abinScience Cat# AY286013, RRID:AB_3729459) |
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| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Background | Receptor tyrosine-protein kinase erbB-2 (Trastuzumab) is a ~137 kDa protein. Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Trastuzumab Idiotypic Antibody (1HE)




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