Anti-Human KDM2A IP Recombinant Antibody (SAA0201) (HP303013)

Name: Anti-Human KDM2A IP Recombinant Antibody (SAA0201)
Brand: abinScience
SKU: HP303013
Price: 126 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HP303013

Species reactivity

Human

Applications

ELISA, IF, IP

Host species

Mouse

Isotype

IgG1

Clone ID

SAA0201

Clonality

Monoclonal

Target

KDM2A, CXXC-type zinc finger protein 8, FBXL11, JHDM1A, FBL7, KIAA1004, F-box protein FBL7, Lysine-specific demethylase 2A, FBL11, [Histone-H3]-lysine-36 demethylase 1A, F-box protein Lilina, JmjC domain-containing histone demethylation protein 1A, F-box/LRR-repeat protein 11, CXXC8, F-box and leucine-rich repeat protein 11

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9Y2K7

RRID

Anti-Human KDM2A IP Antibody (SAA0201) (abinScience Cat# HP303013, RRID:AB_3729735)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Lysine-specific demethylase 2A (KDM2A) is a ~132 kDa protein. Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere.

1. Reischl, S. et al. (2015) Journal of biological rhythms 30, 291-301. PMID: 26037310

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human KDM2A IP Antibody (SAA0201)

References

Datasheet

Anti-Human KDM2A IP Recombinant Antibody (SAA0201).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human KDM2A IP Recombinant Antibody (SAA0201) (HP303013)

Overview

Images

References

Datasheet

SDS

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