Anti-Human PHF8 IP Recombinant Antibody (SAA0216) (HP682013)

Name: Anti-Human PHF8 IP Recombinant Antibody (SAA0216)
Brand: abinScience
SKU: HP682013
Price: 191 USD
Availability: InStock

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50ug
100ug
1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HP682013

Species reactivity

Human

Applications

ELISA, IF, IP

Host species

Mouse

Isotype

IgG2a

Clone ID

SAA0216

Clonality

Monoclonal

Target

[histone H3]-dimethyl-L-lysine(9) demethylase PHF8, KIAA1111, [histone H3]-dimethyl-L-lysine(36) demethylase PHF8, PHF8, ZNF422, Histone lysine demethylase PHF8, PHD finger protein 8

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9UPP1

RRID

Anti-Human PHF8 IP Antibody (SAA0216) (abinScience Cat# HP682013, RRID:AB_3729750)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Histone lysine demethylase PHF8 is a ~117 kDa protein. Histone lysine demethylase with selectivity for mono- and dimethylated residues. It plays an essential role in cell cycle progression and rDNA transcription. Demethylates mono- and dimethylated histone H3 'Lys-9' residue (H3K9Me1 and H3K9Me2) and monomethylated histone H4 'Lys-20' residue (H4K20Me1). Acts as a transcription activator as H3K9Me1, H3K9Me2, H3K27Me2 and H4K20Me1 are epigenetic repressive marks. Displays a very low intrinsic activity toward dimethylated H3 'Lys-27' (H3K27Me2).

1. Loenarz, C. et al. (2010) Human molecular genetics 19, 217-22. PMID: 19843542

2. Zhu, Z. et al. (2010) Cell research 20, 794-801. PMID: 20531378

3. Qiu, J. et al. (2010) Cell research 20, 908-18. PMID: 20548336

4. Liu, W. et al. (2010) Nature 466, 508-12. PMID: 20622854

5. Yu, L. et al. (2010) Cell research 20, 166-73. PMID: 20101266

6. Feng, W. et al. (2010) Nature structural & molecular biology 17, 445-50. PMID: 20208542

7. Kleine-Kohlbrecher, D. et al. (2010) Molecular cell 38, 165-78. PMID: 20346720

8. Qi, HH. et al. (2010) Nature 466, 503-7. PMID: 20622853

9. Horton, JR. et al. (2010) Nature structural & molecular biology 17, 38-43. PMID: 20023638

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human PHF8 IP Antibody (SAA0216)

References

Datasheet

Anti-Human PHF8 IP Recombinant Antibody (SAA0216).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human PHF8 IP Recombinant Antibody (SAA0216) (HP682013)

Overview

Images

References

Datasheet

SDS

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