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Anti-Human TAF1 IP Recombinant Antibody (SAA0232) (HB919013)

Anti-Human TAF1 IP Recombinant Antibody (SAA0232)
Anti-Human TAF1 IP Recombinant Antibody (SAA0232)
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Overview
Catalog No.HB919013
Species reactivityHuman
ApplicationsELISA, IF, IP
Host speciesMouse
IsotypeIgG2a
Clone IDSAA0232
Clonality Monoclonal
Target p250, TAF(II)250, CCGS, BA2R, TAF1, Transcription initiation factor TFIID subunit 1, Cell cycle gene 1 protein, TAFII-250, TAF2A, CCG1, TBP-associated factor 250 kDa, Transcription initiation factor TFIID 250 kDa subunit, TAFII250
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P21675
RRID Anti-Human TAF1 IP Antibody (SAA0232) (abinScience Cat# HB919013, RRID:AB_3729766)
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Transcription initiation factor TFIID subunit 1 (TAF1) is a ~214 kDa protein. The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. TAF1 is the largest component and core scaffold of the TFIID complex, involved in nucleating complex assembly. TAF1 forms a promoter DNA binding subcomplex of TFIID, together with TAF7 and TAF2.

1. Chen, X. et al. (2021) Science (New York, N.Y.) 372. PMID: 33795473
2. Wang, H. et al. (2014) Cell research 24, 1433-44. PMID: 25412659
3. Louder, RK. et al. (2016) Nature 531, 604-9. PMID: 27007846
4. Dikstein, R. et al. (1996) Cell 84, 781-90. PMID: 8625415
Note For research use only.
Images
  • Anti-Human TAF1 IP Recombinant Antibody (SAA0232)

    SDS-PAGE

    SDS-PAGE for Anti-Human TAF1 IP Antibody (SAA0232)

References
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