Anti-Human DNMT1 IP Recombinant Antibody (SAA0251) (HB924013)

Name: Anti-Human DNMT1 IP Recombinant Antibody (SAA0251)
Brand: abinScience
SKU: HB924013
Price: 191 USD
Availability: InStock

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50ug
100ug
1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HB924013

Species reactivity

Human

Applications

ELISA, IF, IP

Host species

Mouse

Isotype

IgG2a

Clone ID

SAA0251

Clonality

Monoclonal

Target

CXXC-type zinc finger protein 9, MCMT, AIM, DNMT1, DNA MTase HsaI, DNMT, DNA (cytosine-5)-methyltransferase 1, Dnmt1, DNA methyltransferase HsaI, M.HsaI, CXXC9

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P26358

RRID

Anti-Human DNMT1 IP Antibody (SAA0251) (abinScience Cat# HB924013, RRID:AB_3729785)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

DNA (cytosine-5)-methyltransferase 1 (DNMT1) is a ~183 kDa protein. DNA methyltransferase that methylates CpG residues. Preferentially methylates hemimethylated DNA. Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly synthesized strand, that is essential for epigenetic inheritance. Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication. It is responsible for maintaining methylation patterns established in development.

1. Schlesinger, Y. et al. (2007) Nature genetics 39, 232-6. PMID: 17200670

2. Pradhan, M. et al. (2008) Biochemistry 47, 10000-9. PMID: 18754681

3. Felle, M. et al. (2011) Nucleic acids research 39, 8355-65. PMID: 21745816

4. Zhang, ZM. et al. (2015) Journal of molecular biology 427, 2520-2531. PMID: 26070743

5. Viré, E. et al. (2006) Nature 439, 871-4. PMID: 16357870

8. Serra, RW. et al. (2014) eLife 3, e02313. PMID: 24623306

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human DNMT1 IP Antibody (SAA0251)

References

Datasheet

Anti-Human DNMT1 IP Recombinant Antibody (SAA0251).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human DNMT1 IP Recombinant Antibody (SAA0251) (HB924013)

Overview

Images

References

Datasheet

SDS

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