

| Catalog No. | HC436014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human IKZF1 Polyclonal Antibody (HC436014) is a rabbit polyclonal antibody detecting IKZF1 in ELISA, IHC, WB. Suitable for Oncorhynchus mykiss, Gallus gallus, Mus musculus, and Human.
Highlights
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| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human IKZF1 (Gly108-Gly231). | ||||||||
| Target | IKZF1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q13422 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Alternate Names | DNA-binding protein Ikaros, Ikaros family zinc finger protein 1, Lymphoid transcription factor LyF-1, IKZF1 | ||||||||
| Background | DNA-binding protein Ikaros (IKZF1) is a ~57 kDa protein. Transcription regulator of hematopoietic cell differentiation. Binds gamma-satellite DNA. Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (fikzfterminal deoxynucleotidyltransferase) gene during thymocyte differentiation. 1. Dijon, M. et al. (2008) Blood 111, 1138-46. PMID: 17934067 2. Ronni, T. et al. (2007) The Journal of biological chemistry 282, 2538-47. PMID: 17135265 3. Kim, JH. et al. (2009) Genome research 19, 533-44. PMID: 19141594 | ||||||||
| Note | For research use only. |
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