

| Catalog No. | HV228014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human PLCB1 Polyclonal Antibody (HV228014) is a rabbit polyclonal antibody detecting PLCB1 in ELISA, IHC, WB. Suitable for Rattus norvegicus, Bovine, Mus musculus, and Human.
Highlights
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| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human PLCB1 (Lys27-Met245). | ||||||||
| Target | PLCB1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9NQ66 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Alternate Names | 1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase beta-1, 3.1.4.11, PLC-154, Phosphoinositide phospholipase C-beta-1, Phospholipase C-I, PLC-I, Phospholipase C-beta-1, PLC-beta-1, PLCB1, KIAA0581 | ||||||||
| Background | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (PLCB1) is a ~138 kDa protein. Catalyzes the hydrolysis of 1-phosphatidylinositol 4,5-bisphosphate into diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) and mediates intracellular signaling downstream of G protein-coupled receptors. Regulates the function of the endothelial barrier. 1. Tall, E. et al. (1997) Biochemistry 36, 7239-48. PMID: 9188725 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-PLCB1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse brain lysate
Lane 2: Rat brain lysate
Lane 3: Rat cerebellum lysate
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