

| Catalog No. | HY195413 | ||||
|---|---|---|---|---|---|
| Species reactivity | Human | ||||
| Applications | ELISA, SPR | ||||
| Host species | Alpaca | ||||
| Isotype | VHH-8His-Cys-tag | ||||
| Clone ID | 2H7 | ||||
| Conjugation | FITC | ||||
| Clonality | Monoclonal | ||||
| Target | Receptor-type tyrosine-protein phosphatase C, 3.1.3.48, Leukocyte common antigen, L-CA, Lymphocyte antigen 5, Ly-5, T200, CD45, Ptprc, Ly-5 | ||||
| Endotoxin level | Please contact with the lab for this information. | ||||
| Associated products | VHH Recombinant Isotype Control Antibody (cAb-Lys2), FITC | ||||
| Accession | P06800 | ||||
| RRID | Anti-Human CD45/PTPRC Nanobody (2H7), FITC (abinScience Cat# HY195413, RRID:AB_3730104) |
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| Form | Liquid | ||||
| Storage buffer | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Background | Receptor-type tyrosine-protein phosphatase C (CD45/PTPRC) is a ~144 kDa protein. Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity. | ||||
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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