

| Catalog No. | HT139010 |
|---|---|
| Description |
InVivoMAb Anti-Human BTN3A1 (20.1) [20.1] (HT139010) is a human monoclonal antibody detecting BTN3A in ELISA, in vivo function (can trigger BTN3A on AML blasts leading to further enhanced Vγ9Vδ2 T cell-mediated killing). Suitable for Human.
|
| Species reactivity | Human |
| Applications | ELISA, in vivo function (can trigger BTN3A on AML blasts leading to further enhanced Vγ9Vδ2 T cell-mediated killing) |
| Host species | Human |
| Isotype | IgG1, kappa |
| Clone ID | 20.1 |
| Clonality | Monoclonal |
| Target | BTN3A, Butyrophilin subfamily 3 member A1, CD277, BTN3A1 |
| Endotoxin level | < 2 EU/mg |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | O00481, O00478, P78410 |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Background | Butyrophilin subfamily 3 member A1 (BTN3A) is a ~57 kDa protein. Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate. |

SDS-PAGE for InVivoMAb Anti-Human BTN3A1 (20.1)
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