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Anti-H4C1 Polyclonal Antibody (HX879024)

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Overview
Catalog No.HX879024
Description
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant human H4C1 (Asn26-Gly103).
Target Histone H4; H4C1; H4/A; H4FA; HIST1H4A; H4C2; H4/I; H4FI; HIST1H4B; H4C3; H4/G; H4FG; HIST1H4C; H4C4; H4/B; H4FB; HIST1H4D; H4C5; H4/J; H4FJ; HIST1H4E; H4C6; H4/C; H4FC; HIST1H4F; H4C8; H4/H; H4FH; HIST1H4H; H4C9; H4/M; H4FM; HIST1H4I; H4C11; H4/E; H4FE; HIST1H4J; H4C12; H4/D; H4FD; HIST1H4K; H4C13; H4/K; H4FK; HIST1H4L; H4C14; H4/N; H4F2; H4FN; HIST2H4; HIST2H4A; H4C15; H4/O; H4FO; HIST2H4B; H4C16; H4-16; HIST4H4
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession P62803, P62804, P84040, P62806, P62805, P62801, P62799, P62802, P70081, P62784, P0CG89, P59259, P62785, P62787, P91849, P62786, Q41811, P35057, P02309
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Histone H4 (H4C1) is a ~11 kDa protein. Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Note For research use only
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Formula
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