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Anti-P2RX1 Polyclonal Antibody (HA787014)

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Overview
Catalog No.HA787014
Description
Anti-P2RX1 Polyclonal Antibody (HA787014) is a rabbit polyclonal antibody detecting P2X purinoceptor 1; P2X1; ATP receptor; Purinergic receptor; P2RX1; P2X1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant human P2RX1 (Gln56-Asp327).
Target P2X purinoceptor 1; P2X1; ATP receptor; Purinergic receptor; P2RX1; P2X1
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession P51575, P51576, P47824
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

P2X purinoceptor 1 (P2RX1) is a ~44 kDa protein. ATP-gated nonselective transmembrane cation channel permeable to potassium, sodium and with relatively high calcium permeability. Furthermore, CTP functions as a weak affinity agonist for P2RX1. Plays a role a role in urogenital, immune and cardiovascular function. Specifically, plays an important role in neurogenic contraction of smooth muscle of the vas deferens, and therefore is essential for normal male reproductive function. In addition, contributes to smooth muscle contractions of the urinary bladder.

1. Bianchi, BR. et al. (1999) European journal of pharmacology 376, 127-38. PMID: 10440098
2. Egan, TM. et al. (2004) The Journal of neuroscience : the official journal of the Society for Neuroscience 24, 3413-20. PMID: 15056721
3. Allsopp, RC. et al. (2010) The Journal of biological chemistry 285, 32770-32777. PMID: 20699225
4. Valera, S. et al. (1995) Receptors & channels 3, 283-9. PMID: 8834001
5. Evans, RJ. et al. (1996) The Journal of physiology 497 ( Pt 2), 413-22. PMID: 8961184
6. Roberts, JA. et al. (2004) The Journal of biological chemistry 279, 9043-55. PMID: 14699168
7. Lecut, C. et al. (2009) Journal of immunology (Baltimore, Md. : 1950) 183, 2801-9. PMID: 19635923
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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