

| Catalog No. | HA803014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-GRM7 Polyclonal Antibody (HA803014) is a rabbit polyclonal antibody detecting Metabotropic glutamate receptor 7; mGluR7; GRM7; GPRC1G; MGLUR7 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant human GRM7 (Gln35-Trp590). | ||||||||
| Target | Metabotropic glutamate receptor 7; mGluR7; GRM7; GPRC1G; MGLUR7 | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q14831, Q68ED2, P35400 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Metabotropic glutamate receptor 7 (GRM7) is a ~102 kDa protein. G-protein coupled receptor activated by glutamate that regulates axon outgrowth through the MAPK-cAMP-PKA signaling pathway during neuronal development. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase that it inhibits. 1. Song, JM. et al. (2021) The Journal of neuroscience : the official journal of the Society for Neuroscience 41, 2344-2359. PMID: 33500274 2. Wu, S. et al. (1998) Brain research. Molecular brain research 53, 88-97. PMID: 9473604 | ||||||||
| Note | For research use only |
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