Anti-Human IFITM1 Polyclonal Antibody (HC024014)

Name: Anti-Human IFITM1 Polyclonal Antibody
Brand: abinScience
SKU: HC024014
Price: 96 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HC024014

Description

Anti-Human IFITM1 Polyclonal Antibody (HC024014) is a rabbit polyclonal antibody detecting Interferon-induced transmembrane protein 1; Dispanin subfamily A member 2a; DSPA2a; Interferon-induced protein 17; Interferon-inducible protein 9-27; Leu-13 antigen; CD225; IFITM1; CD225; IFI17 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant human IFITM1 (His2-His36&Ala58-Asn86&Ser108-Tyr125).

Target

Interferon-induced transmembrane protein 1; Dispanin subfamily A member 2a; DSPA2a; Interferon-induced protein 17; Interferon-inducible protein 9-27; Leu-13 antigen; CD225; IFITM1; CD225; IFI17

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

P13164

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Interferon-induced transmembrane protein 1 (IFITM1) is a ~13 kDa protein. IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronaviruses (SARS-CoV and SARS-CoV-2), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV and SARS-CoV-2 S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration. Inhibits SARS-CoV-2 S protein-mediated syncytia formation.

1. Narayana, SK. et al. (2015) The Journal of biological chemistry 290, 25946-59. PMID: 26354436

2. Shi, G. et al. (2021) The EMBO journal 40, e106501. PMID: 33270927

3. Buchrieser, J. et al. (2020) The EMBO journal 39, e106267. PMID: 33051876

Note

For research use only

Images

Western blot

Lane 1: Jurkat cell lysate
Lane 2: HepG2 cell lysate
Lane 3: K562 cell lysate
Lane 4: HL-60 cell lysate
Lane 5: Hela cell lysate
Lane 6: 293T cell lysate
Lane 7: NIH3T3 cell lysate
Lane 8: MCF-7 cell lysate
Lane 9: Mouse spleen lysate
Lane 10: Mouse testis lysate
Lane11: Mouse brain lysate
Lane12: Rat spleen lysate
Lane13: Rat testis lysate
Lane14: Rat brain lysate

References

Datasheet

Anti-Human IFITM1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

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Anti-Human IFITM1 Polyclonal Antibody (HC024014)

Overview

Images

References

Datasheet

SDS

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