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Anti-RANGAP1 Polyclonal Antibody (HB393014)

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Overview
Catalog No.HB393014
Description
Anti-RANGAP1 Polyclonal Antibody (HB393014) is a rabbit polyclonal antibody detecting Ran GTPase-activating protein 1; RanGAP1; RANGAP1; KIAA1835; SD in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant human RANGAP1 (Gly21-Asp360).
Target Ran GTPase-activating protein 1; RanGAP1; RANGAP1; KIAA1835; SD
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession P46060, P46061
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Ran GTPase-activating protein 1 (RANGAP1) is a ~63 kDa protein. GTPase activator for RAN. Converts cytoplasmic GTP-bound RAN to GDP-bound RAN, which is essential for RAN-mediated nuclear import and export. Mediates dissociation of cargo from nuclear export complexes containing XPO1, RAN and RANBP2 after nuclear export.

1. Takeda, E. et al. (2005) Cell structure and function 30, 69-80. PMID: 16428860
2. Bischoff, FR. et al. (1994) Proceedings of the National Academy of Sciences of the United States of America 91, 2587-91. PMID: 8146159
3. Görlich, D. et al. (1996) The EMBO journal 15, 5584-94. PMID: 8896452
4. Ritterhoff, T. et al. (2016) Nature communications 7, 11482. PMID: 27160050
Note For research use only
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-RANGAP1 Polyclonal Antibody

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