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Anti-Human TMEM108 Polyclonal Antibody (HB401014)

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Overview
Catalog No.HB401014
Description
Anti-Human TMEM108 Polyclonal Antibody (HB401014) is a rabbit polyclonal antibody detecting Transmembrane protein 108; Retrolinkin; TMEM108; KIAA1690; RTLN; UNQ1875/PRO4318 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant human TMEM108 (Glu31-Pro169).
Target Transmembrane protein 108; Retrolinkin; TMEM108; KIAA1690; RTLN; UNQ1875/PRO4318
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q6UXF1
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Transmembrane protein 108 (TMEM108) is a ~59 kDa protein. Transmembrane protein required for proper cognitive functions. Involved in the development of dentate gyrus (DG) neuron circuitry, is necessary for AMPA receptors surface expression and proper excitatory postsynaptic currents of DG granule neurons. Regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transport. Through the interaction with DST, mediates the docking of the dynein/dynactin motor complex to vesicle cargos for retrograde axonal transport. In hippocampal neurons, required for BDNF-dependent dendrite outgrowth.

Note For research use only
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Formula
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