Please ensure Javascript is enabled for purposes of website accessibility
Home > Products > Antibodies > Primary antibodies

Anti-MUC2 Polyclonal Antibody (MX889014)

Price(USD):
Spec:
  • 50ug
  • 100ug
Number:
Get quote
  • Overview

  • Images

  • References

  • Datasheet

  • SDS

Overview
Catalog No.MX889014
Description
Anti-MUC2 Polyclonal Antibody (MX889014) is a rabbit polyclonal antibody detecting Mucin-2; MUC-2; Colonic mucin; MCM; Secreted gel-forming mucin; Muc2 in ELISA, IHC, WB. Suitable for Mouse and Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Species reactivityMouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant mouse MUC2 (Asn31-His350).
Target Mucin-2; MUC-2; Colonic mucin; MCM; Secreted gel-forming mucin; Muc2
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q80Z19, Q62635
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Mucin-2 (MUC2) is a ~479 kDa protein. Coats the epithelia of the intestines and other mucus membrane-containing organs to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of the colon mucus, which is mainly formed by large polymeric networks of MUC2 secreted by goblet cells that cover the exposed surfaces of intestine. MUC2 networks form hydrogels that guard the underlying epithelium from pathogens and other hazardous matter entering from the outside world, while permitting nutrient absorption and gas exchange. Acts as a divalent copper chaperone that protects intestinal cells from copper toxicity and facilitates nutritional copper unptake into cells. Binds both Cu(2+) and its reduced form, Cu(1+), at two juxtaposed binding sites: Cu(2+), once reduced to Cu(1+) by vitamin C (ascorbate) or other dietary antioxidants, transits to the other binding site.

1. Johansson, ME. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 15064-9. PMID: 18806221
2. Johansson, ME. et al. (2009) Journal of proteome research 8, 3549-57. PMID: 19432394
3. Bergstrom, K. et al. (2020) Science (New York, N.Y.) 370, 467-472. PMID: 33093110
Note For research use only
Images
References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommendation

Contact us for custom quotes, bulk requests and any other issues.

Mail: [email protected]

Distributor list