Anti-Mouse PD-1 & CTLA-4 Bispecific Recombinant Antibody (SAA2362) (MC096023)

Name: Anti-Mouse PD-1 & CTLA-4 Bispecific Recombinant Antibody (SAA2362)
Brand: abinScience
SKU: MC096023
Price: 191 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

MC096023

Description

Anti-Mouse PD-1 & CTLA-4 Bispecific Recombinant Antibody (SAA2362) (MC096023) is a mouse monoclonal antibody detecting PD-1 & CTLA-4,PD-1,CTLA-4 in ELISA, in vivo. Suitable for Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Mouse

Applications

ELISA, in vivo

Host species

Mouse

Clonality

Monoclonal

Isotype

IgG2a, kappa

Clone ID

SAA2362

Target

CD279, PD1, PDCD1, Programmed cell death protein 1, Protein PD-1, CD152, CTLA-4, CTLA4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q02242 & P09793

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Danvilostomig is an anti-CTLA4/PDCD1 monoclonal antibody.
• Cancer immunotherapy using checkpoint blockade., PMID:29567705
• The blockade of immune checkpoints in cancer immunotherapy., PMID:22437870
• Immune-related adverse events of checkpoint inhibitors., PMID:32382051
• Immune Checkpoint Blockade in Cancer Therapy., PMID:25605845
• Dermatologic Reactions to Immune Checkpoint Inhibitors : Skin Toxicities and Immunotherapy., PMID:29256113
• Safety profiles of anti-CTLA-4 and anti-PD-1 antibodies alone and in combination., PMID:27141885
• Endocrine Toxicity of Cancer Immunotherapy Targeting Immune Checkpoints., PMID:30184160
• Tumour- and class-specific patterns of immune-related adverse events of immune checkpoint inhibitors: a systematic review., PMID:28945858
• Regulatory mechanisms of immune checkpoints PD-L1 and CTLA-4 in cancer., PMID:34088360
• Fundamental Mechanisms of Immune Checkpoint Blockade Therapy., PMID:30115704

Note

For research use only

Images

SDS-PAGE

SDS-PAGE for Anti-Mouse CTLA4 & PD1 Bispecific Antibody (SAA2362)

References

Datasheet

Anti-Mouse PD-1 & CTLA-4 Bispecific Recombinant Antibody (SAA2362).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Mouse PD-1 & CTLA-4 Bispecific Recombinant Antibody (SAA2362) (MC096023)

Overview

Images

References

Datasheet

SDS

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