Anti-Human ACVR2A Antibody (LAE102) (HB949013)

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50ug
100ug
1mg

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Overview
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Datasheet

Overview

Catalog No.

HB949013

Description

Anti-Human ACVR2A Antibody (LAE102) [LAE102] (HB949013) is a human monoclonal antibody detecting ACVR2A in ELISA, FCM, IF, IHC. Suitable for Human.

Highlights

●Multi-Application — Validated across multiple applications.
●Flow Cytometry — Validated for flow cytometry applications.

Species reactivity

Human

Applications

ELISA, FCM, IF, IHC

Host species

Human

Isotype

IgG1, kapp

Clone ID

LAE102

Clonality

Monoclonal

Target

Activin receptor type-2A, EC:2.7.11.30, Activin receptor type IIA, ACTR-IIA, ACTRIIA, ACVR2A, ACVR2

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P27037

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Activin receptor type-2A (ACVR2A) is a ~57 kDa protein. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A. Mediates induction of adipogenesis by GDF6.

1. Renlund, N. et al. (2007) The Journal of endocrinology 195, 95-103. PMID: 17911401

2. Gray, PC. et al. (2000) The Journal of biological chemistry 275, 3206-12. PMID: 10652306

Note

For research use only

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