

| Catalog No. | HS866023 | ||||||
|---|---|---|---|---|---|---|---|
| Species reactivity | Human, Mouse, Rat | ||||||
| Applications | ELISA, IHC, IP, WB | ||||||
| Host species | Mouse | ||||||
| Isotype | IgG2a, kappa | ||||||
| Clone ID | 96/3 | ||||||
| Clonality | Monoclonal | ||||||
| Target | ICA 512, ICA3, ICA512, ICA512-CCF, ICA512-N-terminal fragment, ICA512-NTF, ICA512-TMF, ICA512-cleaved cytosolic fragment, ICA512-transmembrane fragment, Islet cell antigen 512, Islet cell autoantigen 3, PTP IA-2, PTPRN, R-PTP-N, Receptor-type tyrosine-protein phosphatase-like N | ||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||
| Purity | >95% as determined by SDS-PAGE. | ||||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||||
| Accession | Q16849, Q60673, Q63259 | ||||||
| Form | Liquid | ||||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||
| Background | Receptor-type tyrosine-protein phosphatase-like N (IA-2/PTPRN) is a ~105 kDa protein. Plays a role in vesicle-mediated secretory processes. Required for normal accumulation of secretory vesicles in hippocampus, pituitary and pancreatic islets. Required for the accumulation of normal levels of insulin-containing vesicles and preventing their degradation. Plays a role in insulin secretion in response to glucose stimuli. Required for normal accumulation of the neurotransmitters norepinephrine, dopamine and serotonin in the brain. 1. Harashima, S. et al. (2012) Journal of diabetes investigation 3, 52-61. PMID: 24843546 | ||||||
| Note | For research use only |

SDS-PAGE for Anti-Human IA-2/PTPRN Antibody (96/3)
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