Anti-AAV5 VP1/Capsid protein VP1 Recombinant Antibody (SAA2450) (VK111023)

Name: Anti-AAV5 VP1/Capsid protein VP1 Recombinant Antibody (SAA2450)
Brand: abinScience
SKU: VK111023
Price: 191 USD
Availability: InStock

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Overview

Catalog No.	VK111023
Description	Anti-AAV5 VP1/Capsid protein VP1 Recombinant Antibody (SAA2450) (VK111023) is a rabbit monoclonal antibody detecting VP1 in ELISA, Neutralization, Dot Blot. Suitable for Adeno-associated virus 5 (AAV5). Highlights ●Affinity Purified — Minimal background and high purity for reliable results. ●Multi-Application — Validated across multiple applications.
Species reactivity	Adeno-associated virus 5 (AAV5)
Applications	ELISA, Neutralization, Dot Blot
Host species	Rabbit
Clonality	Monoclonal
Isotype	IgG
Clone ID	SAA2450
Target	VP1, Capsid protein
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	CAA77024.1
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Capsid protein VP1 is a ~81 kDa protein. Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 22 nm in diameter, and consisting of 60 copies of three size variants of the capsid protein VP1, VP2 and VP3 which differ in their N-terminus. The capsid encapsulates the genomic ssDNA. Binds to host cell heparan sulfate and uses host ITGA5-ITGB1 as coreceptor on the cell surface to provide virion attachment to target cell. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Binding to the host receptor also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region and putative nuclear localization signal(s).
Note	For research use only

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Anti-AAV5 VP1/Capsid protein VP1 Recombinant Antibody (SAA2450).pdf

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Anti-AAV5 VP1/Capsid protein VP1 Recombinant Antibody (SAA2450) (VK111023)

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