Anti-Human FUT4 Monoclonal Antibody (1A563) (HB132015)

Name: Anti-Human FUT4 Monoclonal Antibody (1A563)
Brand: abinScience
SKU: HB132015
Price: 106 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD):

Spec:

20ug
50ug
100ug

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.	HB132015
Description	Anti-Human FUT4 Monoclonal Antibody (1A563) [1A563] (HB132015) is a mouse monoclonal antibody detecting FUT4 in ELISA, IHC, WB. Suitable for Human. Highlights ●Recombinant — Superior batch-to-batch reproducibility with defined sequences. ●Multi-Application — Validated across multiple applications.
Species reactivity	Human
Applications	ELISA, IHC, WB
Host species	Mouse
Isotype	IgG
Clone ID	1A563
Clonality	Monoclonal
Immunogen	E. coli - derived recombinant human FUT4 (Asp264-Thr497).
Target	Alpha-(13)-fucosyltransferase 4, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase, EC:2.4.1.152, ELAM-1 ligand fucosyltransferase, Fucosyltransferase 4, Fucosyltransferase IV, Fuc-TIV, FucT-IV, Galactoside 3-L-fucosyltransferase, FUT4
Purification	Protein A/G purified from cell culture supernatant.
Accession	P22083
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Alpha-(1,3)-fucosyltransferase 4 (FUT4) is a ~59 kDa protein. Catalyzes alpha(1->3) linkage of fucosyl moiety transferred from GDP-beta-L-fucose to N-acetyl glucosamine (GlcNAc) within type 2 lactosamine (LacNAc, Gal-beta(1->4)GlcNAc) glycan attached to N- or O-linked glycoproteins. Robustly fucosylates nonsialylated distal LacNAc unit of the polylactosamine chain to form Lewis X antigen (CD15), a glycan determinant known to mediate important cellular functions in development and immunity. Fucosylates with lower efficiency sialylated LacNAc acceptors to form sialyl Lewis X and 6-sulfo sialyl Lewis X determinants that serve as recognition epitopes for C-type lectins. Together with FUT7 contributes to SELE, SELL and SELP selectin ligand biosynthesis and selectin-dependent lymphocyte homing, leukocyte migration and blood leukocyte homeostasis. In a cell type specific manner, may also fucosylate the internal LacNAc unit of the polylactosamine chain to form VIM-2 antigen that serves as recognition epitope for SELE. 1. Goelz, SE. et al. (1990) Cell 63, 1349-56. PMID: 1702034 2. Lowe, JB. et al. (1991) The Journal of biological chemistry 266, 17467-77. PMID: 1716630 3. Mondal, N. et al. (2018) The Journal of biological chemistry 293, 7300-7314. PMID: 29593094 4. Nakayama, F. et al. (2001) The Journal of biological chemistry 276, 16100-6. PMID: 11278338
Note	For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human FUT4 Monoclonal Antibody (1A563)

References

Datasheet

Anti-Human FUT4 Monoclonal Antibody (1A563).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human FUT4 Monoclonal Antibody (1A563) (HB132015)

Overview

Images

References

Datasheet

SDS

Quick access

Contact Us