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Anti-HPV31 Major capsid protein L1 Recombinant Antibody (5F12) (VK120013)

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Overview
Catalog No.VK120013
Species reactivityHuman papillomavirus 31 (HPV31)
ApplicationsELISA-cap, Neutralization
Host speciesMouse
IsotypeIgG1
Clone ID5F12
Clonality Monoclonal
Target L1, Major capsid protein L1
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P17388
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Major capsid protein L1 is a ~56 kDa protein. Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment. This binding mediates a conformational change in the virus capsid that facilitates efficient infection. The virion enters the host cell via endocytosis.

Note For research use only
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