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Anti-HSV gD Recombinant Antibody (E317) (VK413013)

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Overview
Catalog No.VK413013
Description
Anti-HSV gD Recombinant Antibody (E317) (VK413013) is a mouse monoclonal antibody detecting gD in ELISA, Neutralization, IP. Suitable for Human herpesvirus 1 (HHV-1) (Human herpes simplex virus 1) (HSV-1), Human herpesvirus 2 (HHV-2) (Human herpes simplex virus 2) (HSV-2).
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman herpesvirus 1 (HHV-1) (Human herpes simplex virus 1) (HSV-1), Human herpesvirus 2 (HHV-2) (Human herpes simplex virus 2) (HSV-2)
ApplicationsELISA, Neutralization, IP
Host speciesMouse
ClonalityMonoclonal
IsotypeIgG1, kappa
Clone IDE317
Target Envelope glycoprotein D, gD
Endotoxin level < 10 EU/mg as determined by LAL method.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q69091, P03172
Form Liquid
Storage buffer 0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Envelope glycoprotein D (gD) is a ~43 kDa protein. Envelope glycoprotein that binds to the host cell entry receptors NECTIN1, TNFRSF14/HVEM and 3-O-sulfated heparan sulfate, promoting the virus entry into host cells. May trigger fusion with host membrane, by recruiting the fusion machinery composed of gB and gH/gL.

1. Zhang, N. et al. (2011) Nature communications 2, 577. PMID: 22146396
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
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Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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