Anti-Human HBEGF Antibody (KM3966) (HV265033)

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50ug
100ug
1mg

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Overview
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Datasheet

Overview

Catalog No.

HV265033

Description

Anti-Human HBEGF Antibody (KM3966) [KM3966] (HV265033) is a human monoclonal antibody detecting HBEGF in ELISA, FACS, Functional assay. Suitable for Human.

Highlights

●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, FACS, Functional assay

Host species

Human

Isotype

IgG1, kappa

Clone ID

KM3966

Clonality

Monoclonal

Target

DT-R, DTR, DTS, Diphtheria toxin receptor, HB-EGF, HBEGF, HEGFL, Heparin-binding EGF-like growth factor, Proheparin-binding EGF-like growth factor

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q99075

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Proheparin-binding EGF-like growth factor (HBEGF) is a ~23 kDa protein. Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells.

Note

For research use only

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References

Datasheet