Anti-Human APOL1 Polyclonal Antibody (HT291014)

Name: Anti-Human APOL1 Polyclonal Antibody
Brand: abinScience
SKU: HT291014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HT291014

Description

Anti-Human APOL1 Polyclonal Antibody (HT291014) is a rabbit polyclonal antibody detecting APOL1. Suitable for Human.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Immunogen

E. coli - derived recombinant Human APOL1 (Thr227-Leu398).

Target

APOL, APOL1, Apo-L, ApoL, ApoL-I, Apolipoprotein L, Apolipoprotein L-I, Apolipoprotein L1

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Purified by antigen affinity column.

Accession

O14791

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Background

Apolipoprotein L1 (APOL1) is a ~43 kDa protein. May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver. A component of trypanosome lytic factor of human serum; plays a crucial role in killing Trypanosoma brucei by forming pores in parasite lysosomal membranes and sensitizing T.brucei to oxidation-stimulated osmotic lysis.

1. Vanhamme, L. et al. (2003) Nature 422, 83-7. PMID: 12621437

2. Pérez-Morga, D. et al. (2005) Science (New York, N.Y.) 309, 469-72. PMID: 16020735

3. Lecordier, L. et al. (2009) PLoS pathogens 5, e1000685. PMID: 19997494

4. Greene, AS. et al. (2016) The Journal of biological chemistry 291, 3063-75. PMID: 26645690

5. Tytler, EM. et al. (1995) Molecular and biochemical parasitology 69, 9-17. PMID: 7723792

Note

For research use only

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References

Datasheet