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Anti-HEV Papain-like Cysteine Protease/PCP Polyclonal Antibody (VK620044)

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Overview
Catalog No.VK620044
Description
Anti-Hepatitis E virus/HEV Papain-like Cysteine Protease/PCP Polyclonal Antibody (VK620044) is a rabbit polyclonal antibody detecting Putative papain-like cysteine protease. Suitable for Hepatitis E virus genotype 2.
Species reactivityHepatitis E virus (HEV)
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Hepatitis E virus/HEV Papain-like Cysteine Protease/PCP (Thr509-Ala691).
Target EC:2.1.1.-, EC:2.7.7.-, EC:2.7.7.48, EC:3.4.-.-, EC:3.6.4.-, Methyltransferase, NTPase/helicase, Non-structural polyprotein pORF1, PCP, Putative papain-like cysteine protease, Putative protease, RNA-directed RNA polymerase, RdRp
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q03495
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Non-structural polyprotein pORF1 (Papain-like Cysteine Protease/PCP) is a ~185 kDa protein. Methyltransferase: Displays a capping enzyme activity. This function is necessary since all viral RNAs are synthesized in the cytoplasm, and host capping enzymes are restricted to the nucleus. The enzymatic reaction involves a covalent link between 7-methyl-GMP and the methyltransferase, whereas eukaryotic capping enzymes form a covalent complex only with GMP. Methyltransferase catalyzes transfer of a methyl group from S-adenosylmethionine to GTP and GDP to yield m(7)GTP or m(7)GDP. GDP is a better substrate than GTP.

Note For research use only
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Formula
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V₁ (Stock Vol.)
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Anti-HEV Papain-like Cysteine Protease/PCP Polyclonal Antibody

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