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Anti-Yeast HYR1/GPX3 Polyclonal Antibody (JB195014)

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Overview
Catalog No.JB195014
Description
Anti-Yeast HYR1/GPX3 Polyclonal Antibody (JB195014) is a rabbit polyclonal antibody detecting GPX3. Suitable for Yeast.
Species reactivitySaccharomyces cerevisiae (Baker's yeast)
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Yeast HYR1/GPX3 (Met1-Glu163).
Target EC:1.11.1.24, GPX3, GPx 3, Glutathione peroxidase homolog 3, Glutathione peroxidase-like peroxiredoxin HYR1, HYR1, Hydrogen peroxide resistance protein 1, ORP1, Oxidant receptor peroxidase 1, PHGPx3, Phospholipid hydroperoxide glutathione peroxidase 3
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession P40581
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Glutathione peroxidase-like peroxiredoxin HYR1 (GPX3) is a ~18 kDa protein. Involved in oxidative stress response and redox homeostasis. Functions as a sensor and transducer of hydroperoxide stress. In response to hydroperoxide stress it oxidizes (activates) the transcription activator YAP1, which is involved in transcription activation of genes of the oxidative stress response pathway. May also play a direct role in hydroperoxide scavenging, being the most active of three closely related S.cerevisiae peroxiredoxins (GPX1, GPX2, and HYR1/GPX3) with respect to peroxide and lipid hydroperoxide reduction. The three enzymes are not required for the glutaredoxin-mediated antioxidant function.

Note For research use only
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Formula
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C₂ (Working Conc.)
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Anti-Yeast HYR1/GPX3 Polyclonal Antibody

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