

| Catalog No. | HD640014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human GJA8 Polyclonal Antibody (HD640014) is a rabbit polyclonal antibody detecting GJA8. Suitable for Human.
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human GJA8 (Gly225-Val433). | ||||||||
| Target | Connexin-50, Cx50, GJA8, Gap junction alpha-8 protein, Lens fiber protein MP70 | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P48165 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Background | Gap junction alpha-8 protein (GJA8) is a ~48 kDa protein. Structural component of eye lens gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane. Small molecules and ions diffuse from one cell to a neighboring cell via the central pore. 1. Arora, A. et al. (2008) Journal of medical genetics 45, 155-60. PMID: 18006672 2. Graw, J. et al. (2009) Molecular vision 15, 1881-5. PMID: 19756179 | ||||||||
| Note | For research use only |
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