

| Catalog No. | HC548014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human FLNC Polyclonal Antibody (HC548014) is a rabbit polyclonal antibody detecting FLNC. Suitable for Rat, Mouse, and Human.
Highlights
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| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human FLNC (Glu17-Lys259). | ||||||||
| Target | ABP-280-like protein, ABP-L, ABPL, Actin-binding-like protein, FLN-C, FLN2, FLNC, FLNc, Filamin-2, Filamin-C, Gamma-filamin | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q14315 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Background | Filamin-C (FLNC) is a ~291 kDa protein. Muscle-specific filamin, which plays a central role in sarcomere assembly and organization. Critical for normal myogenesis, it probably functions as a large actin-cross-linking protein with structural functions at the Z lines in muscle cells. May be involved in reorganizing the actin cytoskeleton in response to signaling events. 1. Agarwal, R. et al. (2021) Circulation research 129, 751-766. PMID: 34405687 | ||||||||
| Note | For research use only |
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