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Anti-Human LRIF1 Polyclonal Antibody (HD601014)

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Overview
Catalog No.HD601014
Description
Anti-Human LRIF1 Polyclonal Antibody (HD601014) is a rabbit polyclonal antibody detecting LRIF1. Suitable for Human.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human LRIF1 (His190-Asn311).
Target C1orf103, HBiX1, HP1-binding protein enriched in inactive X chromosome protein 1, LRIF1, Ligand-dependent nuclear receptor-interacting factor 1, RIF1, Receptor-interacting factor 1
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q5T3J3
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Ligand-dependent nuclear receptor-interacting factor 1 (LRIF1) is a ~84 kDa protein. Together with SMCHD1, involved in chromosome X inactivation in females by promoting the compaction of heterochromatin. Also able to repress the ligand-induced transcriptional activity of retinoic acid receptor alpha (RARA), possibly through direct recruitment of histone deacetylases. Also required for silencing of the DUX4 locus in somatic cells.

1. Nozawa, RS. et al. (2013) Nature structural & molecular biology 20, 566-73. PMID: 23542155
2. Li, HJ. et al. (2007) Journal of cellular biochemistry 102, 1021-35. PMID: 17455211
3. Hamanaka, K. et al. (2020) Neurology 94, e2441-e2447. PMID: 32467133
Note For research use only
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Formula
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Anti-Human LRIF1 Polyclonal Antibody

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