Anti-Human C2 Polyclonal Antibody (HY106014)

Name: Anti-Human C2 Polyclonal Antibody
Brand: abinScience
SKU: HY106014
Price: 168 USD
Availability: InStock

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Overview
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Datasheet
SDS

Overview

Catalog No.

HY106014

Description

Anti-Human C2 Polyclonal Antibody (HY106014) is a rabbit polyclonal antibody detecting Human C2. Suitable for Human.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human C2 (Ile245-His451).

Target

C2, C3/C5 convertase, Complement C2, Complement C2a, EC:3.4.21.43, Serine protease complement C2b

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

P06681

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Background

Complement C2 is a ~83 kDa protein. Precursor of the catalytic component of the C3 and C5 convertase complexes, which are part of the complement pathway, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. Component C2 is part of the classical, lectin and GZMK complement systems.

1. Rawal, N. et al. (2003) The Journal of biological chemistry 278, 38476-83. PMID: 12878586

2. Milder, FJ. et al. (2006) Structure (London, England : 1993) 14, 1587-97. PMID: 17027507

3. Rawal, N. et al. (2008) The Journal of biological chemistry 283, 7853-63. PMID: 18204047

4. Donado, CA. et al. (2025) Nature 641, 211-221. PMID: 39914456

5. Lan, F. et al. (2025) Nature 638, 490-498. PMID: 39814882

6. Héja, D. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, 10498-503. PMID: 22691502

Note

For research use only

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References

Datasheet