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Anti-Human ING5 Polyclonal Antibody (HD420014)

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Overview
Catalog No.HD420014
Description
Anti-Human ING5 Polyclonal Antibody (HD420014) is a rabbit polyclonal antibody detecting ING5. Suitable for Human and Mouse.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human ING5 (Ala2-Ala105).
Target ING5, Inhibitor of growth protein 5, p28ING5
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q8WYH8
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Inhibitor of growth protein 5 (ING5) is a ~27 kDa protein. Component of the HBO1 complex, which specifically mediates acetylation of histone H3 at 'Lys-14' (H3K14ac) and, to a lower extent, acetylation of histone H4. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Through chromatin acetylation it may regulate DNA replication and may function as a transcriptional coactivator. Inhibits cell growth, induces a delay in S-phase progression and enhances Fas-induced apoptosis in an INCA1-dependent manner.

1. Lalonde, ME. et al. (2013) Genes & development 27, 2009-24. PMID: 24065767
2. Doyon, Y. et al. (2006) Molecular cell 21, 51-64. PMID: 16387653
3. Shiseki, M. et al. (2003) Cancer research 63, 2373-8. PMID: 12750254
4. Zhang, F. et al. (2011) PloS one 6, e21505. PMID: 21750715
Note For research use only
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
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Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-Human ING5 Polyclonal Antibody

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